Abstrak: The research of immunomodulatory activity and leucocyte cell counts of white male mice has been done by using red dragon fruit peel (Hylocereus lemairei (Hook.) Britton & Rose) extracts. Animals were divided into 4 groups, which consists of only one group was given a NaCMC supension, 2, 3, and 4 group in extract red dragon fruit peel with a dose of 10 mg/kg BB, 50 mg/kg BB dan 100 mg/kg BB. Extracts are given for 6 days orally. The result of research showed given the extract red dragon fruit peel orally of male mice for 6 days can improve the constants and phagocytosis index, and increasing the dose 100 mg/kg BB. The activity of the red dragon fruit peel extract also increased the counts of cells and the total counts of leukocytes was significantly (P <0,05). A dose of 100 mg/kg BB is the best dose improve the immunomodulatory activity and leukocyte cell counts.
Kata Kunci: Hylocereus lemairei (Hook.); Britton & Rose; Immunomodulatory; Leukocyte Cell
Penulis: Havizur Rahman, Yufri Aldi, Elda Mayanti
Kode Jurnal: jpfarmasidd160613
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