Abstrak: Study about the influence of agarwood leave’s extract (Aquilaria malaccensis Lam.) on the formation of atherosclerosis in male quail (coturnic-coturnix japonica) induced high fat feeding and prophylthiourasil. Animal experiments were grouped into 5 consisting of Group I as a negative control only given food strander, group II as a positive control and PTU given MLT groups III, IV, V given leaf extract of aloes with a dose of 100 mg / kg BW, 300 mg / kg BW, 900 mg / kg BW and, along with the MLT and PTU the extract was given orally once a day for 60 day. The doses used were 100, 300, 900 mg/kg body weight respectively. Control groups was given food standar. Result showed that the administration of the agarwood leaf extract could prevent formation of atherosclerosis in male quail significantly (P < 0.05). The optimal effect showed doses 100 mg/kg BW.
Kata Kunci: leaf extracts agarwood; atherosclerosis; MLT (high fat food) and PTU (propilthiourasil)
Penulis: Suhatri, Dian Zaini Putra, Elisma
Kode Jurnal: jpfarmasidd140523
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