Abstrak: The formulation of leaf´s murbey ethanol extract´s toothpaste and its activities against dental plaque´s bacteries had been done. Pre test showed the leaf´s murbey ethanol extracts at 4% of concentration gave an optimal diameter of inhibition against dental plague. Based that fact, this research would have made 3 formulas at toothpaste from leaf´s murbey extract at 1%, 2%, and 4% of concentration. All of formulas would have wade with the same base of toothpaste. All of formulas would be characterized of pharmaceutic´s properties and antibacteria´s activities, that would be compared with toothpaste “S” and “P” as a standard. The result shawed all formulas gave a good characteristic of pharmaceutic properties. F3 had gave a good diameter of inhibition, that was 21.875 mm, where as the “S” and “P” of toothpaste had gave a diameter of inhibition respectively 23.875 mm and 22.75mm. There was a significant difference of inhibition´s diameter of all formulas at 0.05 level of confidence.
Kata Kunci: murbey ethanol extract´s; toothpaste; anti-plaque
Penulis: Akmal Djamaan, Fatimah Saidah, Rina Wahyuni
Kode Jurnal: jpfarmasidd140525
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