PENGARUH PEMBERIAN PROBIOTIK Weisella paramesenteroides ISOLAT DADIAH SEBAGAI ANTI DIARE PADA MENCIT (Mus muscullus)

Abstract:The effect of probiotic Weisella paramesenteroides was isolated from dadiah may effect as antidiarrhea has been investigated. Dadiah is tradisonal food of west sumatera region. The purpose of the research is to determine the effect of using probiotic Weisella paramesenteroides from dadiah Sitingkai-Palupuah, Agam Sumatera Barat related to frequency of bowel, microflora usus and histolgi of villus ileum. The experiment was done with  five treatments and two repeating.

The results of this experiment showing the use of  probiotic Weisella paramesenteroides was different as significant interaction (p<0,01). In reducing the frequency of bowel, microflora balance and the high of ileum villus also conformed. The use of probiotic Weisella paramesenteroides was able to reduce the frequency of bowel after 24 hours observation. The highest mean of LAB total colony by supplementation E.coli and Weisella paramesenteroides  was 2x10⁸ cfu/ml at 28,50x10⁷ cfu/gr. The highest mean of E.coli total colony by supplementation E.coli only at 14.63x10⁷ cfu/gr. And the highest measurement villus by Weisella paramesenteroidestreated was 2x10⁸ cfu/ml at 267,85 μm.

Keywords: diarrhea, probiotic, Weisella paramesenteroides, microflora balance, villus of intestines

Penulis:Reno Purnama Zalni, Sumaryati Syukur, Endang Purwati

Kode Jurnal: jpkimiadd130086

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