Abstract: The effects of electric cigarette exposure on lung tissue of mice were studied. The experiments using completely randomized design (CRD) with 3 treatments, i.e. treatment of electric cigarette with strawberry flavour, tobacco flavour, and control treatment that was not exposed to cigarette smoke. Eight male mice were used for each group. Exposure treatment was done every day for 2 consecutive weeks with dosage of 20 times suction using syringe of 60 mL. After receiving treatment for 2 weeks, the mice were killed by cervical dislocation. Lung organ was isolated and prepared histologically using paraffin method and then stained with haematoxylin and eosin (HE). Result showed, treatment mice lose weight significantly (p< 0.05). In gross anatomy, electric cigarrete smoke affect lung feature, but histological observation showed that membrane damage, damage to the lumen and the relationship between alveoli were statistically unsignificant (p>0.05). In summary, short period exposure to electric cigarette smoke tends to induce injury to lung at anatomical level, but in several histological aspects electric cigarette treatment has no significant effect on lung tissue.
Keywords: alveolar lumen, alveolar membrane, electric cigarettes
Penulis: Nanin Triana, Syafruddin Ilyas dan Salomo Hutahaean
Kode Jurnal: jpbiologidd130006
Share This :
comment 0 komentar
more_vert