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ISOLASI SENYAWA TRITERPENOID DARI FRAKSI AKTIF KULIT BATANG KECAPI (Sandoricum koetjape Merr) DAN UJI BIOAKTIFITAS BRINESHRIMPS LETHALITY BIOASSAY

ISOLASI SENYAWA TRITERPENOID DARI FRAKSI AKTIF KULIT BATANG KECAPI (Sandoricum koetjape Merr) DAN UJI BIOAKTIFITAS BRINESHRIMPS LETHALITY BIOASSAY
Abstract: This study has identified a triterpenoid compound in ethyl acetate extract from the stem bark of Sandoricum koetjape Merr with cytotoxic activities further explored previously. The triterpenoid compound contained in ethyl acetate extract of Sandoricum koetjape Merr was analyze under Liebermann-Burchard, resulting in reddish. The compound gave  252,4 – 253,6oC in melting point test. Based on Brine Shrimps Lethality Bioassay test, LC50 value of ethyl acetate extract was 164,437 μg/ml. Analysis with UV-Vis produces the maximum absorption peak at 204 nm refer to presence of double bond (not conjugate). Analysis IR spectroscopy gives absorption at 3220 cm-1 (-OH), 2931 cm-1 (C-H), 1705 cm-1 (C=O), 1190 cm-1 (C-O), 1384 cm-1 and 1458 cm-1 (gem-dimethyl)
Keywords: Sandoricum koetjape Merr, triterpenoid, toxicity, Brineshrimps Lethality
Penulis: Whendy Aria Utama, Mai Efdi, dan Adlis Santoni
Kode Jurnal: jpkimiadd130088
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